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We treated hepatocytes with auranofin, which inhibits redox-active selenoproteins, including thioredoxin reductases and, at the dose used here, glutathione peroxidases 1, 2, 3, 4, and 6 (Chaudiere and Tappel, 1984, Roberts and Shaw, 1998, Scarbrough et al., 2012)

FIGURE 2 The second category regroups prodrugs non-structurally related to GSH

CYP2A6 comprises around 4% of hepatic CYP content that has a relatively small active site and metabolizes substances such as nicotine, coumarin, letrozole, tegafur, and several other pharmaceuticals (Tornio and Backman, 2018)

It actually plays a very real role in keeping your nerves working, your brain sharp and your blood healthy

The benzyl alcohol doesn't prevent oxidation

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