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Functional Characterisation and Permeation Studies of Lyophilised Thiolated Chitosan Xerogels for Buccal Delivery of Insulin

The compound promotes apoptosis in cancer cells by activating key caspases (caspase-3, -8, and -9) and increasing intracellular ROS, which signals apoptotic cell death

Depression in older adults

Impairments in neuronal survival mediated by HMGB1 are believed to be closely associated with the glycolytic pathway, as evidenced by the mitigation of these adverse effects through treatment with the glycolysis inhibitor 2-DG [194]

10.1101/gad.947102 23 BodeA

However, the feasibility of using it to treat metabolic disorders and neurodegenerative diseases is currently under investigation in clinical trials (Liu Y