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cLDs and other cytoplasmic materials in the gonad core flow toward and into expanding oocytes at the proximal end of the gonad
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52 Oral ingestion of forskolin stimulates chloride and water secretion into the intestinal lumen, reduces water reabsorption, and causes decreased smooth muscle relaxation and cAMP modulation in the intestines, contributing to diarrhea
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However, any interpretation of such studies must be under the caveat that staging/grading of MPNSTs is not consistent across trials, which complicates comparison
