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Lung epithelial cell-derived extracellular vesicles activate macrophage-mediated inflammatory responses via ROCK1 pathway

doi: 10.1126/scitranslmed.aaa9301 70 GiannoukakisNPhillipsBFinegoldDHarnahaJTruccoM

27 Consistent with the lack of mitochondrial involvement, erastin did not cause ATP depletion, and morphologically, mitochondria appeared smaller and denser, but not swollen or ruptured as seen in classical necrotic cell death

For instance, learning how NAC (N-Acetyl-l-Cysteine) supports detoxification is essential, as NAC provides the precursor building blocks needed to restore intracellular glutathione levels and protect the mitochondria from further mycotoxin-induced injury

2011;10(1, article 11) doi: 10.1186/1475-2891-10-11

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