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Description
The transcription start site, directed by the HSP1 promoter, is at the phenylalanine tRNA (tRNA Phe )
In clinical advancement, strategies with more realistic value include local delivery or use as adjuvant therapy, rather than relying on long-term systemic exposure

[DOI] [PubMed] [Google Scholar] 19.Meister A
10.1016/j.morpho.2015.12.003 Morphologie 40 FedericoA.DallioM.GravinaA

Oxidative stress and reactive oxygen species: a review of their role in ocular disease
ISCs are involved in electron transport, substrate binding, enzymatic catalysis and play critical roles in maintaining genomic stability since several DNA polymerases and helicases require interaction with ISCs for proper functioning
