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RNAseq analysis of the ER-IP samples revealed strong enrichment (adjusted P value 99.97%

Dudek, M

Vial fell or was shaken accidentally If a reconstituted vial was shaken vigorously (dropped, thrown in a bag, held by a toddler), some peptide degradation may have occurred

In a rabbit model in which the primary lacrimal gland, sclerotial gland, and cornea were removed to induce dry eye, esculetin (0.05% of the diet) was able to inhibit the expression of IL-1, IL-1, and TNF- by inhibiting the ERK1/2 signaling pathway and thereby suppressing IL-1, IL-1, and TNF- (96)

Fode M, Snksen J, McPhee SJ, Ohl DA

Gordin A, Goldenberg D, Golz A, Netzer A, Joachims HZ