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The correct dosage can avoid overstimulation
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Glial reactivity or CNS inflammation could also retroact on the metabolism in ME/CFS since inflammatory stimulation or broadly restricted perfusion may cause mitochondrial dysfunction
Levallois C, Maini JC, & Balmes JL (1987) Sensitivity of human lymphocytes to acetaldehyde: comparison between alcoholic and control subjects
Furthermore, any potential lightening effects are likely to be minimal and temporary, rather than a permanent change in skin tone
