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The Tregs can be divided into 2 subpopulations, CD38 + Tregs that make up approximately 90% of the total Treg population and are more potent in suppressing T cell proliferation, and CD38 - Tregs

doi: 10.1016/j.ijantimicag.2009.10.009 [DOI] [PubMed] [Google Scholar] 179

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Three compounds dominate the published research: BPC-157 (a gastric pentadecapeptide with unusual protease resistance), TB-500 (a synthetic fragment of thymosin beta-4), and GHK-Cu (a copper-binding tripeptide with broad ECM-modulating effects)