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Also after Cd exposure in liquid culture PC levels were induced in a time and concentration dependent manner, whereas a less pronounced stimulation was found after Cu exposure [39,40]

rda:

These are exposure biomarkers showing the chemical exposure and biologically active dosage, effect biomarkers containing information on structural and functional changes such as firstly-observed clinical symptoms and genotoxins causing DNA damage, individual sensitivity biomarkers responsible of enzymes affecting cancer

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For cardiovascular applications, this steadier exposure might provide more stable vascular effects compared to once-daily peaks and troughs