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For all other applications, SS-31 remains an investigational compound

Hepatic deiodinase activity is dispensable for the maintenance of normal circulating thyroid hormone levels in mice
Lipoperoxidation is the main biochemical event during ferroptosis, which requires high amounts of free Fe 2+ in the cytosol to generate ROS by Fenton reaction [74]

doi: 10.1002/advs.202105451 255 ZhouHLiuZZhangZPandeyNKAmadorENguyenWet al
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Clin Exp Pediatr
