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doi: 10.1016/0006-291x(89)91141-8

Notably, elevated levels of 12(S)-hydroxyeicosatetraenoic acid [12(S)-HETE], a subclass of eicosanoids, activate the intracellular cation channel transient receptor potential vanilloid one and mediate endothelial dysfunction in DM (Otto et al., 2020)

Protective effects of Lycium barbarum polysaccharide on male sexual dysfunction and fertility impairments by activating hypothalamic pituitary gonadal axis in streptozotocin-induced type-1 diabetic male mice

The environmental samples were analysed in a local laboratory, while the drugs were sent to the AEMPS, (Spanish Agency for the Medicines and Health Products)

It could therefore be speculated that MGO-associated reduced insulin signaling might affect viability and morphology of astrocytes in close proximity to the cerebral vasculature, leading to a remodeling of the perivascular space and a loss of neurovascular coupling