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J Immunol (Baltimore Md: 1950) (2018) 201(1):27895

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The differentiation of somatotroph cell is governed by the pituitary transcription factor 1 (Pit-1)

From the study of new phenyl dihydrouracil (PD)-based PROTACs designed by this group, PD-PROTAC 113 (SJ43489) stands out, capable of degrading the LCK protein (DC 50 = 0.8 nM) and inhibiting the cell viability of KOPT-K1 cells with nanomolar potency (IC 50 = 37 nM) 156

To assess bacterial degradation of heavy GSH, we pretreated AGS cells with 50 g/mL [2- 13 C 1 ]-Gly for 24 h, then washed the cells to remove exogenous [2- 13 C 1 ]-Gly prior to infection with WT, gGT , or gGT :: gGT H