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extract causes hepatic atrophy in transgenic models and dysregulates genes involved in bile acid transport and lipid metabolism, suggesting a mechanism linked to metabolic imbalance ( Enydra fluctuans Lour., can induce marked hepatocyte vacuolation at high doses (Xavier and Kripasana, 2020)

Zhang M

Veerbeek JM, Langbroek-Amersfoort AC, van Wegen EEH, et al

doi: 10.1111/jam.14472

doi: 10.1016/S0151-9638(11)70087-4

Small RNAs from stress-related pathways are over-represented in EVs isolated from human GBM patients as well as miRNA related to dopamine metabolism Lobeline interacts with both VMAT2 and the dopamine transporter (DAT) and through these interactions can modulate dopamine storage and release [37, 38]