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Notably, case reports and series have described severe cholestatic jaundice as an initial manifestation of hyperthyroidism, which often resolves with antithyroid therapy or radioiodine (I-131) ablation following restoration of euthyroidism[18,19]

Exosomal miR-146a-5p derived from human umbilical cord mesenchymal stem cells can alleviate antiphospholipid antibody-induced trophoblast injury and placental dysfunction by regulating the TRAF6/NF-B axis

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As the ICH E19 framework gains traction globally, sponsors and ( Contract Research Organizations ) CROs that adopt (Selective Safety Data Collection) SSDC strategically will be better positioned to run leaner, more impactful trials