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Micrornas and other non-coding rnas in adipose tissue and obesity: emerging roles as biomarkers and therapeutic targets

In Figure 1, the theoretical calculation of the impact of GSHs artificial oxidation on GSSG rise is shown, considered their actual ratio in blood (e.g., 500:1)

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To understand whether RSC stimulation is confined to one of the two cohesin loader modules, we repeated the nucleosome sliding assays in the presence of either Scc2C or Scc4-Scc2N

Glutathione is a linear tripeptide of L-glutamine, L-cysteine, and glycine

Obesity is a predominantly pro-inflammatory process, and the main mechanism is that in obesity, classically activated macrophages (M1) have higher concentrations than alternatively activated macrophages (M2), expressing pro-inflammatory cytokines, and activating pro-inflammatory pathways, such as the JNK and TNF-kB signaling pathways, which lead to low-grade chronic inflammation throughout the body (190)
