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They are responsible for the incretin effect which causes insulin release and post prandial glucose clearance after a meal

JAMA 2009;302:97784
Biochemical assessments of peripheral blood from AD patients demonstrated significantly elevated levels of the mitochondrial fission factor Fis1, with postmortem brain specimens further revealing upregulated Drp1 expression in AD cases (Pakpian et al., 2020)

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[PDF] tubitak.gov.tr Zhao, Alex Tang, et al

However, a PTHrP 134 maintains a less pronounced anabolic effect to the bone and osteoblasts possibly due its higher clearance rate [52, 53]
