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10.3389/fmicb.2016.00185 365

In contrast, an increase in sub-visible particle count was seen after 21 days, and an increase in ThT fluorescence was seen after 28 days, in the case of co-formulation 1 containing HP-B-CD (Average MS: 0.92)

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The effects might be additive, synergistic, or potentially counteractive depending on specific circumstances
