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At P12, when catagen is induced in the Ctnnb1 mutant, Dkk2 and Notum remain undetectable, and this lack of expression persists throughout the premature catagen phase of the Ctnnb1 mutant (Supplementary Fig
No published data contradicts these timelines, but no published data specifically validates them either
KOR is the same as MOR, which is heavily involved in the integration of reinforcement and aversion stimuli including severe and acute pain, and is mainly distributed in the brainstem, midbrain, and forebrain [28,29,30]
Thus, erdosteine not only prevents the accumulation of free oxygen radicals when their production is accelerated, but also increases antioxidant cellular protective mechanisms [60]
