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Separate high-dose oral b12 (1000 to 2000 mcg daily) or regular b12 injections (1000 mcg weekly or monthly) offer more reliable repletion

Nanomaterials and neurodegeneration

Aug 2 2011;2(4):318-323

This hypothesis is supported by the observation that LPS induced -globin and -globin in vaginal epithelium, indicating that the induction of -globin might be a component of immune activation in epithelial cells

They can occur spontaneously or may be induced by electrical stimulation, nerve ischemia, percussion of the nerve, or needle movement (22