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Important Notice GHK-Cu (Copper Peptide) is intended for laboratory research purposes only
This mutation in mice nicely recapitulates the human vascular EDS phenotype, including thin and fragile skin, aortic aneurysm and rupture, and abnormal collagen fibrillogenesis in skin, aorta, and bowel

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Collagen and matrix biology The first published paper documenting collagen synthesis stimulation by GHK-Cu appeared in 1988: fibroblast cultures increased collagen output when exposed to GHK-Cu at concentrations as low as 10 M, with peak activity around 1 nM (Maquart et al., FEBS Letters, 1988)
