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This synergy is thought to result from complementary intracellular signalling mechanisms GHRH receptor activation increases cAMP via Gs coupling, while ghrelin receptor activation increases intracellular calcium and activates protein kinase C via Gq/11 coupling

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Cell 52 541553 Gong T, Yang Y, Jin T, Jiang W and Zhou R 2018 Orchestration of NLRP3 inflammasome activation by ion fluxes

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Cannabidiol enhjances anandamide signalling and alleviates psychotic symptoms of schizophrenia

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