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Description
Mechanistic tool in preclinical work: Used to explore lipid and glucose metabolism pathways in controlled models of energy balance

Clinical trials demonstrate considerable weight loss in patients with obesity or Type 2 diabetes

Understanding why this occursfrom metabolic adjustment and nutrient demands to injection site reactionshelps distinguish expected responses from complications requiring medical attention

J Med Chem (2019) 62(23):1078397

Selective NNMT inhibitor (5-amino-1MQ) reduces adiposity in DIO mice

We additionally defined patients as having these diseases if they had already been diagnosed at other hospitals, or based on their clinical records prior to the current admission, because laboratory data obtained at one point in time might be affected by medications or dietary treatment
