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We also theorize that due to the relatively short-half-life of MT-II (approximately 2 hours), once or twice daily dosing may not be sufficient to meet a threshold at which effective neuro-modulation may occur in adult C57BL/6J mice

As a result of lipid peroxidation a great variety of aldehydes can be produced, including hexanal, malondialdehyde (MDA) and 4-hydroxynonenal (Catala, 2006)

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