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First, the free acid of bromoheptanoic acid 40 is protected by a prenyl group, then prenyl nitroheptanoate 42 is generated and the Henry nitroaldol step was performed with 1,1,3,3 tetramethylguanidine (TMG) and nonanal

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[DOI] [Google Scholar] 81.Sattler J., Hesterberg R., Lorenz W., Schmidt U., Crombach M., Stahlknecht C.D