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Oral administration of a humid extract of dehydrated leaves is used to treat menorrhagia and diabetes in Australia, and oral administration of an extract of root bark is used to treat fever (9, 88)

The N-terminal tryptophan residue is critical for biological activity, as deletion or modification significantly reduces DSIPs effects in research models

These observations allowed postulating that intracellular redox state of the thiol pool, which strongly depends on GSH level, can drive autophagic response at multiple levels (Filomeni et al., 2010)

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Side effects may include mild nausea, fatigue, and temporary mineral depletion