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Are there safe alternatives to kojic acid for skin lightening during pregnancy

Consult dermatologists or other qualified healthcare providers for evidence-based approaches to specific skin concerns

333 A clinical study in 121 patients after coronary artery bypass grafting showed that curcuminoid capsules administered at a dose of 4 g/day provided a cardioprotective effect by suppressing surgery-associated myocardial infarction (MI), CRP, MDA, and N-terminal pro-B-type natriuretic peptide (NT-proBNP)

However, its long-term safety has not been established, and it should not be taken for longer than 12 weeks at a time due to the potential risk of liver and kidney damage

[DOI] [PMC free article] [PubMed] [Google Scholar] 93.Hsieh M.J., Lee C.H., Chueh H.Y., Chang G.J., Huang H.Y., Lin Y., Pang J.S

The median duration of treatment was 164 days for capecitabine-treated patients and 145 days for 5-FU/LV-treated patients