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Within the United States, probiotic regulation falls under the authority of the FDA, which generally classifies these products as dietary supplements or food ingredients in accordance with the Dietary Supplement Health and Education Act (DSHEA) of 1994 (566)

Its role becomes particularly significant when considering the context of radiation-induced brain injuries [48]

It binds to cell surface receptors and activates intracellular signaling cascades that upregulate collagen I, collagen III, and fibronectin production

This can be the most dangerous stage as seizures and other health complications may arise

Skin changes appear after 48 weeks