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An important unresolved question in this context is whether parts of the type IV pilus machinery, such as the minor pilins and the pilin PilA, act as a piston to push the EPS slime out of the PilQ gate, as has been suggested 108

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Forschungsmodelle deuten darauf hin, dass die Hexarelin-Signalgebung Folgendes umfassen kann: Aktivierung der Phospholipase C (PLC) Bildung von IP- und DAG-Botenstoffen Intrazellulre Kalziumfreisetzung Aktivierung der Proteinkinase C (PKC) Daher ist Hexarelin besonders relevant fr Studien zu kurzfristiger hormoneller Pulsdynamik und rezeptorvermittelter endokriner Signalgebung

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