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Access of the HMG coenzyme A substrate is thus prevented because of the presence of the statin in the binding pocket of the enzyme, 13 ultimately inhibiting both mevalonic acid and cholesterol synthesis (Figure)

Fibrolamellar Hepatocellular Carcinoma: Mechanistic Distinction From Adult Hepatocellular Carcinoma Pediatr Blood Cancer 63 7: 1163-7

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