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Description
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Supplied strictly for research use only , it is not for therapeutic, human, or veterinary application
Clinically relevant NRF2-modulating agents currently include MMF (approved for relapsing forms of MS), diroximel fumarate (approved for relapsing forms of MS), tegomil fumarate (approved for RRMS by the EMA in 2025), and omaveloxolone (approved for Friedreichs ataxia
RNA sequencing can uncover new biomarkers and therapeutic targets that might not be identified otherwise by evaluating gene expression during the activation or suppression of autophagy, especially in clinical samples
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