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MMPs also digest the ECM, releasing ECM-bound growth factors, which in turn attract inflammatory cells that express additional growth factors to drive angiogenesis

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[DOI] [PMC free article] [PubMed] [Google Scholar] 67.Johnson S.K., Fitza M.A., Lerner D.A., Calhoun D.M., Beldon M.A., Chan E.T., Johnson P.T.J

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However, the causal relationships among microbial dysbiosis, immune dysregulation, and disease onset remain elusive