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Vitamin B12 injections are generally safe, but some individuals may experience side effects, including: Pain or redness at the injection site Mild diarrhea Itching Nausea or vomiting Dizziness or headaches Hot flashes In rare cases, more serious reactions, such as allergic responses (rash, swelling, trouble breathing), can occur

J Diabetes Metab Disord

But oral Vitamin B12 supplements do have some limitations: Lower Absorption: For individuals with certain health conditions, such as gastrointestinal disorders or those who have undergone bariatric surgery, oral supplements may not be absorbed as effectively as injections

Contact your GP immediately, call NHS 111, or attend A&E if you develop: Irregular heartbeat or palpitations that persist Chest pain or pressure Severe breathlessness Significant leg swelling These symptoms require assessment to determine their cause, which may or may not be related to your B12 treatment

Higher is not always better: 9 mg often delivers a better efficacy-to-tolerability ratio than 12 mg

A second collagenase injection was administered three days later