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However, the largest Phase IIb trial involving 536 participants failed to demonstrate statistically significant weight loss compared to placebo at the primary 12-week endpoint, leading to development termination in 2007
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doi: 10.1016/j.bbalip.2022.159151 41 WangYZengFZhaoZHeLHeXPangHet al
This damage is frequently associated with alterations in gut microbial diversity and abundance ( According to Schaefer et al

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