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Medical therapeutics Levodopa/Carbidopa In 1961, Hornykiewicz was the first to introduce the use of levodopa to increase dopamine levels and improve PD symptoms

This may support the design of future clinical trials to better define patient populations (98)

The combination of gene expression and metabolic profiling will provide more detailed and sensitive toxicological assessment of NPs (Shim et al., 2012)

The angiotensin IV analog Nle-Tyr-Leu--(CH2-NH2)3-4-His-Pro-Phe (Norleual) can act as a hepatocyte growth factor/c-Met inhibitor