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All experimental animals were housed under standardized specific pathogen-free (SPF) conditions with environmental enrichment at the Animal Experimental Center of Hainan Medical University, with a temperature of 25 2 C, humidity of 65 5%, and a 12 h light/12 h dark cycle, with free access to food and water

- Use 2 times/day morning and night after other skincare steps such as toner, emulsion or lotion steps

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Neves GYS, Marchiosi R, Ferrarese MLL, Siqueira-Soares RC, Ferrarese-Filho O

Do not refrigerate or freeze unless specifically instructed by your pharmacist