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The cell-level mechanism is now confirmed by two independent labs

Effects of fructooligosaccharides (FOS) on growth, survival, gut microflora, stress, and immune response in Pacific white shrimp, Litopenaeus vannamei, cultured in a recirculating system

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J Neurosci 19(16):71007110 Traversy MT, Vandal M, Tremblay C, Tournissac M, Gigure-Rancourt A, Bennett AD, Calon F (2017) Altered cerebral insulin response in transgenic mice expressing the epsilon-4 allele of the human apolipoprotein E gene
