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Normal platelet activation may cause a shift in the redox state

show that blocking this pathway by targeting the glutamine importer ASCT2 (SLC1A5) decreases tumorigenesis in mouse leukaemia models while largely sparing normal haematopoiesis

Antoni, L., Nuding, S., Wehkamp, J., & Stange, E

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Ferroptosis-related molecules metabolic pathways can regulate glutathione state, cysteine exploitation, lipid peroxidation, nicotinamide adenine dinucleotide phosphate function and iron homeostasis