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For facial use, we recommend our dedicated face serums and creams

use it as a night cream

(2015) 10:e0123013

Entacapone is a reversible inhibitor of COMT, while tolcapone is a reversible inhibitor of both COMT and another enzyme called COMT-B

Consequently, cellular metabolism is suppressed, leading to necrosis of factors associated with glycolysis and hypoxia

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