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and the absence of such a study is a genuine gap, not a clean bill of health

found that mitophagy-inducing coumarin (MIC) prolonged the lifespan of Caenorhabditis elegans in an HLH-30/TFEB-dependent and mitophagy-dependent manner involving DCT-1/BNIP3 and also prevented mitochondrial dysfunction in mammalian cells ( The antimicrobial capacity of coumarins has been demonstrated in previous studies

2024;134(10): e173278

As early as 2009, we briefly discussed the relationship between excitotoxicity and neurodegenerative diseases [8]

PMID: 27450738 | doi:10.1016/bs.vh.2016.04.005 Mendias CL et al