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The first reaction is catalyzed by serine hydroxymethyltransferase (SHMT), specifically SHMT1 (in the cytoplasm) and SHMT2 (in the mitochondria)

10.1158/0008-5472.CAN-07-1764 64 SantivasiW
Zataria multiflora Boiss and carvacrol affect 2-adrenoceptors of guinea pig trachea

Investigative Dermatology 117 (1), 315
