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Hammond BR Jr, Wooten BR, Snodderly DM
Like fetal brain development, during the development of brain organoids, several cell types with a specific regional identity are generated, and this is due to several sequential trajectories of cell differentiation (Kim and Chang, 2023)
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This study suggested that the inhibition of CXCR1/CXCR2 combined with standard taxane therapy, in addition to potentiating the taxane antitumor activity, can reduce paclitaxel-induced neurotoxicity, thus giving some insight for the development of novel treatments [131]
Changes in brain homeostasis cause changes in microglia motility and morphology [33]
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