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Like leptin treatment, sustainability of these anti-obesity effects is still not clear

Taken together, these data demonstrate the feasibility of Drosophila for the study of acetaminophen toxicity, bringing with it an ease of genetic and microbiome manipulation, high-throughput screening, and availability of transgenic animals
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Protective effect of dietary curcumin and capsaicin on induced oxidation of low-density lipoprotein, iron-induced hepatotoxicity and carrageenan-induced inflammation in experimental rats

Moreover, Nrf2 knockout mice were more sensitive to chronic stress than their wild-type counterparts, highlighting the critical role of the Nrf2 cytoprotective response in mitigating depression [146]

When the body accumulates excess fat, it can trigger systemic inflammation and insulin resistance
