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While NOX2 plays a role in the killing of bacteria and fungi, it enhances the pathology caused by viruses of low and high pathogenicity, including influenza A viruses [100]
J., Kaelber, D
doi:10.1007/s00441019030168
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Exercise-induced IL-6, mainly from skeletal muscle, may inhibit pro-inflammatory cytokines like TNF and IL-1 and stimulate anti-inflammatory mediators
Nevertheless, research and development programs for new antimicrobial agents are considered unattractive investments for pharmaceutical companies
