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Acknowledgments AMG 966 Study 20160316 was sponsored by Amgen

Conversely, lowland migrants who experience acute mountain sickness frequently demonstrate gut dysbiosis characterized by reduced microbial diversity and proliferation of opportunistic pathogens ( 2 Gut microbiota 2.1 Composition and function of gut microbiota The gut microbiota refers to the microbial communities residing in the human gastrointestinal tract, primarily composed of bacteria, archaea, fungi, and viruses, with bacteria being the main focus of research

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doi: 10.1016/j.isci.2024.109542

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Additionally, inflammatory conditions can influence this regulation resulting in alterations in the mucosal barrier