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This suggests that metal-induced stimulation of GR is insufficient to cope with the massive GSH-consuming effects (direct metal-GSH binding, GSH oxidation, PC synthesis), causing a reduction in free reduced GSH

We present detailed descriptions of each statistical test and the sample sizes for each figure in Supplementary Table S2

[DOI] [PMC free article] [PubMed] [Google Scholar] 40.Zinc Deficiency, Excess and Supplementation

Healthy skin cells should be nurtured rather than destroyed

As previously described, MEL is a neurohormone with antioxidant properties