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These systems may represent new horizons for compounds that have not been clinically tested thus far or that have previously failed in clinical settings as potential ATs

Furthermore, the level of -globin gene expression under the control of LCR enhancers is subject to position effects [162], [163]

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FG-4592, a hypoxia-inducible factor-prolyl hydroxylase inhibitor, has been found to elevate intracellular GSH levels and decrease iron accumulation when administered as a pre-treatment (166)

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