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SIRT5 is responsible for removing malonylation from enzymes in the glycolytic pathway, thereby enhancing enzyme activity and promoting glycolysis
Also, it is documented that in neurodegenerative diseases regional hypometabolism, oxidative stress, and altered metabolism of fatty acids and glucose occur

doi: 10.1158/1078-0432.CCR-10-1453

The free fatty acids generated by lipophagy promote adenosine 5-triphosphate generation through oxidation in mitochondria

Linn) on the damages induced by nicotine in rats as compared to alpha-tocopherol

S.KrasnowR.MichelM.NishitaD.ContiD