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Amino acids 108129 appear to show high mitogenic activity

Studies also indicate its ability to enhance injury recovery and counteract the signs of aging [7, 8]

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This difference may be explained by the results of in vitro binding studies, which showed that daratumumab can directly bind CD38 on RBCs, whereas isatuximab requires a cofactor (e.g., a mouse anti-CD38 antibody or a CD38 inhibitor), suggesting masking of the isatuximab epitope on RBCs in some patients [49, 50]