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218,219 Targeting H 2 S biosynthesis The inhibition of H 2 S biosynthesis has been shown to sensitise cancer cells to chemotherapy, as it disturbs the mitochondrial equilibrium by impairing bioenergetics
In fact, the levels of several of the metabolites in the TSP and OCM pathways differed between individuals with ALD, active drinkers without liver disease, and healthy controls
CONCLUSIONS Both 1-day and 21-day initiation regimens were generally well tolerated, with safety profiles through 4 weeks consistent with the known profiles for aripiprazole and AL
Similar to previous studies that have found excessive accumulation of oxidized PUFA-containing lipids can induce ferroptosis, acidic cancer cells exposed to PUFAs also undergo ferroptosis [220]
Tummers QR, Hoogstins CE, Gaarenstroom KN, de Kroon CD, van Poelgeest MI, Vuyk J, et al
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