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When -glutamyl-p-nitroanilide is used as the substrate for hydrolysis, the formation step of the acyl enzyme is faster than the step for the water-conducted breakdown of the intermediate, as shown by the faster reaction rate for the transpeptidation reaction compared with that of hydrolysis [86]

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TM30338, a dual Y 2 -Y 4 receptor agonist that leads to an acute reduction in food intake, and TM30339, a selective Y 4 receptor agonist, which is likely to be the subject of phase I/II study in the near future

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Glucocorticoid-induced skeletal muscle atrophy in vitro is attenuated by mechanical stimulation

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